Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ESRRB | O95718 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834013 | 0.90 | ELANE (0.41) | ELANEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL17834010 | 0.82 | ELANE (0.54) | ELANENPC1ESRRBSMN1; SMN2MEN1 | |
| SCHEMBL17834011 | 0.79 | ELANE (0.43) | ELANENPC1ESRRBKDM4EMEN1 | |
| SCHEMBL17834009 | 0.71 | RAB9A (0.53) | ELANERAB9AHPGDNPC1ALDH1A1 | |
| SCHEMBL4680703 | 0.70 | ELANE (0.61) | ELANEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19862709 | 0.70 | ELANE (0.61) | ELANERAB9AALDH1A1MAPTLMNA | |
| SCHEMBL18868773 | 0.70 | RAB9A (0.64) | ELANERAB9AHPGDNPC1ALDH1A1 | |
| SCHEMBL7906121 | 0.69 | ATM (0.48) | ELANEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL650209 | 0.69 | ATM (0.51) | ELANEHPGDNPC1ALDH1A1MAPT | |
| SCHEMBL825544 | 0.69 | ELANE (0.71) | ELANERAB9ANPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160169920-A1 | ION SENSOR | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160169920-A1 | ION SENSOR | ORAI1, CACNA1E, NCS1 | ELANE 3815/4885HDAC3 1796/4885HDAC4 916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.