Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 9/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CHAT | P28329 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024779 | 0.86 | NFE2L2 (0.30) | NFE2L2 | |
| SCHEMBL3064012 | 0.85 | DDAH1 (0.33) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL8013516 | 0.81 | LMNA (0.32) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL8013513 | 0.81 | LMNA (0.32) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL3437884 | 0.80 | LMNA (0.55) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL373961 | 0.80 | ALDH1A1 (0.44) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL29726936 | 0.76 | IDO1 (0.41) | LMNAIDO1TSHRCYP1A2RAB9A | |
| SCHEMBL1880902 | 0.76 | IDO1 (0.41) | LMNAIDO1TSHRCYP1A2RAB9A | |
| SCHEMBL17836940 | 0.74 | NFE2L2 (0.44) | NFE2L2TRPA1MEN1KMT2ATSHR | |
| SCHEMBL20584026 | 0.73 | NFE2L2 (0.39) | NFE2L2TRPA1CYP1A2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10391418-B2 | Apparatus for vacuum purification | MERCK PATENT GMBH (DE) | 2019-08-27 | — | — | US | disclosed |
| US-20180207545-A1 | APPARATUS FOR VACUUM PURIFICATION | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| US-9937438-B2 | Method for vacuum purification | MERCK PATENT GMBH (DE) | 2018-04-10 | — | — | US | disclosed |
| US-20160175736-A1 | METHOD FOR VACUUM PURIFICATION | MERCK PATENT GMBH (DE) | 2016-06-23 | — | — | US | disclosed |
| EP-3033155-A1 | METHOD FOR VACUUM PURIFICATION | Merck Patent GmbH (DE) | 2016-06-22 | — | — | EP | disclosed |