Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17835456 | 0.85 | NFE2L2 (0.40) | IDO1MEN1LMNATHRBBLM | |
| SCHEMBL7024779 | 0.77 | NFE2L2 (0.30) | — | |
| SCHEMBL373961 | 0.76 | ALDH1A1 (0.44) | IDO1MEN1LMNATHRBBLM | |
| SCHEMBL3437884 | 0.76 | LMNA (0.55) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL8013516 | 0.73 | LMNA (0.32) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL8013513 | 0.73 | LMNA (0.32) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL31055736 | 0.73 | LMNA (0.44) | DDAH1MEN1LMNATHRBBLM | |
| SCHEMBL8217394 | 0.73 | LMNA (0.44) | DDAH1MEN1LMNATHRBBLM | |
| SCHEMBL1880902 | 0.73 | IDO1 (0.41) | IDO1LMNATSHR | |
| SCHEMBL29726936 | 0.73 | IDO1 (0.41) | IDO1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100228038-A1 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-09-09 | — | — | US | disclosed |
| US-7667055-B2 | Processes for the production of polycyclic fused ring compounds | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-02-23 | — | — | US | disclosed |
| US-7550608-B2 | Processes for the preparation of docetaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-7541458-B2 | β-lactam synthesis | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| CN-101243061-A | Processes for the preparation of docetaxel | UNIV FLORIDA STATE RES FOUND (US) | 2008-08-13 | — | — | CN | disclosed |
| CN-101243060-A | Processes for the preparation of paclitaxel | UNIV FLORIDA STATE RES FOUND (US) | 2008-08-13 | — | — | CN | disclosed |
| EP-1919926-A2 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS | Florida State University Research Foundation, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| US-7358378-B2 | Processes for the preparation of paclitaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2008-04-15 | — | — | US | disclosed |
| EP-1893594-A2 | PROCESSES FOR THE PREPARATION OF PACLITAXEL | Florida State University Research Foundation, Inc. (US) | 2008-03-05 | — | — | EP | disclosed |
| EP-1888522-A2 | ß-LACTAM SYNTHESIS | Florida State University Research Foundation, Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006135656-A2 | PROCESSES FOR THE PREPARATION OF PACLITAXEL | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-21 | — | — | WO | disclosed |
| WO-2006135655-A2 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-21 | — | — | WO | disclosed |
| WO-2006135670-A2 | β-LACTAM SYNTHESIS | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-21 | — | — | WO | disclosed |
| US-20060281934-A1 | Processes for the production of polycyclic fused ring compounds | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | US | disclosed |
| US-20060281933-A1 | Processes for the preparation of paclitaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | US | disclosed |
| US-20060281932-A1 | Processes for the preparation of docetaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | US | disclosed |
| US-20060281914-A1 | Beta-lactam synthesis | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | US | disclosed |
| EP-0690856-A4 | — | UNIV NEW YORK (US) | 1996-02-07 | — | — | EP | disclosed |
| EP-0690856-A1 | ANTI-TUMOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARATION THEREOF AND FOR TREATMENT | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022856-A1 | ANTI-TUMOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARATION THEREOF AND FOR TREATMENT | THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) | 1994-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281934-A1 | Processes for the production of polycyclic fused ring compounds | COASY, PARG, PIN4 | DDAH1 2212/4885IDO1 4211/4885MEN1 179/4885 |
| US-20060281933-A1 | Processes for the preparation of paclitaxel | PDCD10, PDS5B, CASP10 | DDAH1 468/4885IDO1 4177/4885MEN1 2846/4885 |
| US-20100228038-A1 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS | COASY, PARG, PIN4 | DDAH1 2212/4885IDO1 4211/4885MEN1 179/4885 |
| US-20060281914-A1 | Beta-lactam synthesis | COASY, MANBA, DCXR | DDAH1 1633/4885IDO1 1543/4885MEN1 100/4885 |
| US-20060281932-A1 | Processes for the preparation of docetaxel | PDCD10, PDS5B, DHCR7 | DDAH1 317/4885IDO1 3977/4885MEN1 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.