Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942903 | 0.94 | ALDH1A1 (0.37) | ALDH1A1TSHRTHPOTHRBBLM | |
| SCHEMBL6567442 | 0.86 | ALDH1A1 (0.32) | ALDH1A1TSHRTHPO | |
| SCHEMBL6567440 | 0.86 | ALDH1A1 (0.32) | ALDH1A1TSHRTHPO | |
| SCHEMBL10738083 | 0.86 | ALDH1A1 (0.32) | ALDH1A1TSHRTHPO | |
| SCHEMBL7620117 | 0.86 | TSHR (0.33) | ALDH1A1TSHRTHPOTHRBBLM | |
| SCHEMBL6263196 | 0.86 | TSHR (0.33) | ALDH1A1TSHRTHPOTHRBBLM | |
| SCHEMBL6263199 | 0.86 | TSHR (0.33) | ALDH1A1TSHRTHPOTHRBBLM | |
| SCHEMBL11283607 | 0.84 | CA4 (0.30) | ALDH1A1CA4 | |
| SCHEMBL9651326 | 0.84 | TDP1 (0.33) | ALDH1A1BLMPMP22 | |
| SCHEMBL11283609 | 0.84 | CA4 (0.30) | ALDH1A1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273901-B2 | Process of forming a pyrrole compound | Nanyang Technical University (SG) | 2012-09-25 | — | — | US | disclosed |
| US-8273901-B2 | Process of forming a pyrrole compound | Nanyang Technical University (SG) | 2012-09-25 | — | — | US | disclosed |
| US-8273901-B2 | Process of forming a pyrrole compound | Nanyang Technical University (SG) | 2012-09-25 | — | — | US | disclosed |
| US-20110124881-A1 | PROCESS OF FORMING A PYRROLE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2011-05-26 | — | — | US | disclosed |
| US-20110124881-A1 | PROCESS OF FORMING A PYRROLE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2011-05-26 | — | — | US | disclosed |
| US-20110124881-A1 | PROCESS OF FORMING A PYRROLE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2011-05-26 | — | — | US | disclosed |
| US-7470786-B2 | Method for manufacture of ceftriaxone sodium | LUPIN LIMITED (IN) | 2008-12-30 | — | — | US | disclosed |
| US-20080200670-A1 | METHOD FOR THE MANUFACTURE OF CEFTRIAXONE SODIUM | LUPIN LIMITED (RESEARCH PARK) (IN) | 2008-08-21 | — | — | US | disclosed |
| US-20070049749-A1 | Method for Manufacture of Ceftriaxone Sodium | LUPIN LIMITED (RESEARCH PARK) (IN) | 2007-03-01 | — | — | US | disclosed |
| US-20070015917-A1 | Method For Manufacture of Ceftriaxone Sodium | LUPIN LIMITED (RESEARCH PARK) (IN) | 2007-01-18 | — | — | US | disclosed |
| EP-1274677-B1 | METHOD FOR PRODUCING OXIME ETHERS | BASF AG (DE) | 2007-01-17 | — | — | EP | disclosed |
| US-6680410-B2 | ALKYLATION IN PRESENCE OF APROTIC SOLVENT | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-20 | — | — | US | disclosed |
| US-20030109740-A1 | Method for producing oxime ethers | BASF AKTIENGESELLSCHAFT (DE) | 2003-06-12 | — | — | US | disclosed |
| EP-1274677-A1 | METHOD FOR PRODUCING OXIME ETHERS | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-15 | — | — | EP | disclosed |
| EP-1117636-B1 | METHOD FOR PREPARING TRION-BIS(OXIME ETHER) DERIVATIVES ANDRION-MONO AND TRION-BIS(OXIME ETHER) DERIVATIVES OBTAINED THEREWITH | BASF AG (DE) | 2002-12-11 | — | — | EP | disclosed |
| US-6441236-B1 | HYDROLYSIS, AMINATION | BASF AKTIENGESELLSCHAFT (DE) | 2002-08-27 | — | — | US | disclosed |
| WO-2001077070-A1 | METHOD FOR PRODUCING OXIME ETHERS | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-18 | — | — | WO | disclosed |
| EP-1117636-A1 | METHOD FOR PREPARING TRION-BIS(OXIME ETHER) DERIVATIVES ANDRION-MONO AND TRION-BIS(OXIME ETHER) DERIVATIVES OBTAINED THEREWITH | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000018726-A1 | METHOD FOR PREPARING TRION-BIS(OXIME ETHER) DERIVATIVES ANDRION-MONO AND TRION-BIS(OXIME ETHER) DERIVATIVES OBTAINED THEREWITH | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124881-A1 | PROCESS OF FORMING A PYRROLE COMPOUND | OXER1, OGDH, OPRD1 | ALDH1A1 67/4885TSHR 1794/4885THPO 3528/4885 |
| US-20030109740-A1 | Method for producing oxime ethers | HCCS, NOS2, CBR3 | ALDH1A1 2594/4885TSHR 574/4885THPO 4292/4885 |
| US-20070049749-A1 | Method for Manufacture of Ceftriaxone Sodium | TREH, CHAT, MRPL21 | ALDH1A1 1915/4885TSHR 3097/4885THPO 1925/4885 |
| US-20070015917-A1 | Method For Manufacture of Ceftriaxone Sodium | TREH, CHAT, MRPL21 | ALDH1A1 1915/4885TSHR 3097/4885THPO 1925/4885 |
| US-20080200670-A1 | METHOD FOR THE MANUFACTURE OF CEFTRIAXONE SODIUM | CHAT, TREH, MRPL21 | ALDH1A1 1869/4885TSHR 3037/4885THPO 2073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.