Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TLR4 | O00206 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 5/20 | 0.36 |
| ▸ | NOS1 | P29475 | 5/20 | 0.36 |
| ▸ | NOS2 | P35228 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2888263 | 0.95 | TLR4 (0.40) | ALDH1A1KMT2ATLR4CYP2C9NOS3 | |
| SCHEMBL2888265 | 0.95 | TLR4 (0.40) | ALDH1A1KMT2ATLR4CYP2C9NOS3 | |
| SCHEMBL9013274 | 0.91 | CYP1A2 (0.42) | ALDH1A1KMT2ATLR4CYP2C9CYP1A2 | |
| SCHEMBL2689965 | 0.91 | NOS3 (0.40) | ALDH1A1KMT2ATLR4CYP2C9NOS3 | |
| SCHEMBL9013281 | 0.91 | CYP1A2 (0.42) | ALDH1A1KMT2ATLR4CYP2C9CYP1A2 | |
| SCHEMBL1666553 | 0.87 | TLR4 (0.51) | ALDH1A1KMT2ATLR4CYP2C9NOS3 | |
| SCHEMBL1666552 | 0.87 | TLR4 (0.51) | ALDH1A1KMT2ATLR4CYP2C9NOS3 | |
| SCHEMBL8215701 | 0.87 | TLR4 (0.51) | ALDH1A1KMT2ATLR4CYP2C9NOS3 | |
| SCHEMBL7912286 | 0.86 | TLR4 (0.44) | ALDH1A1KMT2ATLR4CYP2C9CYP1A2 | |
| SCHEMBL7912304 | 0.86 | TLR4 (0.44) | ALDH1A1KMT2ATLR4CYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 728 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400784-A1 | Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition | LG CHEM, LTD. (KR) | 2024-12-05 | — | — | US | claimed |
| US-20240392094-A1 | Method for Screening Solvent for Polyvinyl Chloride Extraction, Recycling Method for Waste Material, and Recycled Polyvinyl Chloride and Composition | LG CHEM, LTD. (KR) | 2024-11-28 | — | — | US | claimed |
| CN-118026995-A | Dihydrotriazole aromatization precursor and application thereof in deacylating and arylating reaction of ketone | 国科大杭州高等研究院 | 2024-05-14 | — | — | CN | claimed |
| CN-117897439-A | Method for screening solvent for extraction of polyvinyl chloride, method for recovering waste material, and recovered polyvinyl chloride and composition | 株式会社LG化学 | 2024-04-16 | — | — | CN | claimed |
| CN-117897440-A | Method for screening solvent for extraction of polyvinyl chloride, method for recycling waste material, recycled polyvinyl chloride and composition | 株式会社LG化学 | 2024-04-16 | — | — | CN | claimed |
| CN-117126178-A | Bisphenol thiazide compound and synthesis method thereof | 湘潭大学 | 2023-11-28 | — | — | CN | claimed |
| WO-2023033601-A1 | METHOD FOR SCREENING SOLVENT FOR POLYVINYL CHLORIDE EXTRACTION, RECYCLING METHOD FOR WASTE MATERIAL, AND RECYCLED POLYVINYL CHLORIDE AND COMPOSITION | 주식회사 엘지화학 | 2023-03-09 | — | — | WO | claimed |
| WO-2023033605-A1 | METHOD FOR SCREENING SOLVENT FOR EXTRACTING POLYVINYL CHLORIDE, METHOD FOR RECYCLING WASTE, RECYCLED POLYVINYL CHLORIDE, AND COMPOSITION | 주식회사 엘지화학 | 2023-03-09 | — | — | WO | claimed |
| CN-115197055-A | Method for synthesizing 4-propylcyclohexanone by continuous flow microreactor | 湖南华腾医药有限公司 | 2022-10-18 | — | — | CN | claimed |
| CN-109438318-B | Synthesis method of 3-aryl indole and derivatives thereof | 湖南医药学院 | 2022-05-03 | — | — | CN | claimed |
| CN-107417705-A | Imidazo [2,1 b] benzothiazole compound and its synthetic method | 湘潭大学 | 2017-12-01 | — | — | CN | claimed |
| WO-2015061804-A1 | PRODUCTION OF RENEWABLE FINE CHEMICALS AND LIQUID FUELS | PURDUE RESEARCH FOUNDATION (US) | 2015-04-30 | — | — | WO | claimed |
| CN-102241576-B | Method for preparing 2,2'-di(4-ketocyclohexyl) propane by catalytic oxidation | NANTONG BAISHENG CHEMICAL CO LTD | 2013-05-29 | — | — | CN | claimed |
| US-8383637-B2 | 2-amino-quinazoline derivatives useful as inhibitors of β-secretase (BACE) | JANSSSEN PHARMACEUTICA N.V. (BE) | 2013-02-26 | — | — | US | claimed |
| CN-102241576-A | Method for preparing 2,2'-di(4-ketocyclohexyl) propane by catalytic oxidation | NANTONG BAISHENG CHEMICAL CO LTD | 2011-11-16 | — | — | CN | claimed |
| EP-1776349-B1 | 2-AMINO-QUINAZOLINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE) | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-06 | — | — | EP | claimed |
| CN-101035771-A | 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE) | JANSSEN PHARMACEUTICA NV (BE) | 2007-09-12 | — | — | CN | claimed |
| EP-1776349-A2 | 2-AMINO-QUINAZOLINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE) | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-04-25 | — | — | EP | claimed |
| US-20060079687-A1 | Novel 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE) | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-04-13 | — | — | US | claimed |
| WO-2006017836-A2 | 2-AMINO-QUINAZOLINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE) | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-02-16 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079687-A1 | Novel 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE) | BACE2, BACE1, APP | ALDH1A1 2650/4885KMT2A 2035/4885TLR4 4827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.