Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 17/20 | 0.45 |
| ▸ | CA1 | P00915 | 17/20 | 0.45 |
| ▸ | CA2 | P00918 | 17/20 | 0.45 |
| ▸ | CA9 | Q16790 | 15/20 | 0.45 |
| ▸ | CA4 | P22748 | 15/20 | 0.45 |
| ▸ | CA7 | P43166 | 10/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 10/20 | 0.45 |
| ▸ | CA5A | P35218 | 9/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 9/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17838827 | 0.86 | KMT2A (0.47) | MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL17838887 | 0.86 | GPR119 (0.54) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL17853443 | 0.81 | CA2 (0.44) | CA12CA1CA2CA9CA4 | |
| Hydrochloric Acid SCHEMBL17838889 | 0.81 | CA2 (0.43) | CA12CA1CA2CA9CA4 | |
| SCHEMBL28426546 | 0.79 | CCR5 (0.44) | CA12CA1CA2CA9CA4 | |
| SCHEMBL17838888 | 0.77 | CHIT1 (0.51) | — | |
| SCHEMBL17838879 | 0.74 | STS (0.48) | MEN1KMT2A | |
| SCHEMBL29101926 | 0.72 | LTA4H (0.47) | MEN1KMT2AALDH1A1 | |
| SCHEMBL17838870 | 0.71 | MEN1 (0.46) | MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL27200509 | 0.71 | CA2 (0.70) | MEN1KMT2AALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428720-B | Substituted aminotriazoles as inhibitors of acid mammalian chitinase | 昂科艾伦迪治疗法股份公司 | 2020-06-30 | — | — | CN | disclosed |
| EP-3233832-B1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS SA (PL) | 2019-11-20 | — | — | EP | disclosed |
| EP-3233832-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS S.A. (PL) | 2017-10-25 | — | — | EP | disclosed |
| US-20160368894-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2016-12-22 | — | — | US | disclosed |
| US-9440953-B2 | Substituted amino triazoles useful as acidic mammalian chitinase inhibitors | OncoArendi Therapeutics Sp. z o.o. (PL) | 2016-09-13 | — | — | US | disclosed |
| US-20160176843-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2016-06-23 | — | — | US | disclosed |
| WO-2016099311-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160176843-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | CHIA, CHIT1, CMA1 | MEN1 3425/4885KMT2A 4066/4885ALDH1A1 2011/4885 |
| US-20160368894-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | CHIA, CHIT1, CMA1 | MEN1 3425/4885KMT2A 4066/4885ALDH1A1 2011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.