Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3503724 | 0.88 | MAPT (0.45) | SMN1; SMN2LMNAMAPTMAPK1NPSR1 | |
| SCHEMBL5200606 | 0.82 | MEN1 (0.38) | SMN1; SMN2LMNAL3MBTL1MAPTMAPK1 | |
| SCHEMBL17844158 | 0.79 | GAA (0.43) | SMN1; SMN2L3MBTL1MAPTMAPK1KDM4E | |
| SCHEMBL5198203 | 0.79 | CASP3 (0.43) | SMN1; SMN2LMNAL3MBTL1MAPTMAPK1 | |
| SCHEMBL17844161 | 0.78 | FAAH (0.44) | SMN1; SMN2LMNAL3MBTL1MAPTNPSR1 | |
| SCHEMBL17844142 | 0.76 | GAA (0.38) | SMN1; SMN2LMNAL3MBTL1MAPTNPSR1 | |
| SCHEMBL19127998 | 0.75 | POLB (0.44) | SMN1; SMN2LMNAMAPTMAPK1NPSR1 | |
| SCHEMBL17844198 | 0.75 | MEN1 (0.48) | SMN1; SMN2LMNAMAPTNPSR1ALDH1A1 | |
| SCHEMBL5184388 | 0.74 | FAAH (0.47) | SMN1; SMN2LMNAL3MBTL1MAPTMAPK1 | |
| SCHEMBL17844174 | 0.74 | FAAH (0.40) | L3MBTL1MAPTNPSR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |