Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844158 | 0.88 | GAA (0.43) | GAAALDH1A1GLAATML3MBTL1 | |
| SCHEMBL5186011 | 0.86 | ALDH1A1 (0.48) | GAAALDH1A1GLAATML3MBTL1 | |
| SCHEMBL5607253 | 0.86 | MAPT (0.38) | ALDH1A1NPSR1FAAHMGLLLMNA | |
| SCHEMBL17844161 | 0.78 | FAAH (0.44) | GAAALDH1A1GLAATML3MBTL1 | |
| SCHEMBL5198203 | 0.78 | CASP3 (0.43) | GAAALDH1A1GLAATML3MBTL1 | |
| SCHEMBL17844140 | 0.76 | SMN1; SMN2 (0.49) | GAAALDH1A1L3MBTL1NPSR1LMNA | |
| SCHEMBL17844220 | 0.76 | FAAH (0.40) | GAAALDH1A1GLAATML3MBTL1 | |
| SCHEMBL17844070 | 0.76 | FAAH (0.40) | GAAALDH1A1GLAATML3MBTL1 | |
| SCHEMBL17844198 | 0.76 | MEN1 (0.48) | GAAALDH1A1ATMNPSR1FAAH | |
| SCHEMBL5614183 | 0.76 | P2RX3 (0.37) | GAAALDH1A1L3MBTL1BACE1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |