Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | NRP1 | O14786 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.33 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.33 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.33 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844229 | 0.85 | MEN1 (0.48) | TAAR1MEN1KMT2ACASP3CASP7 | |
| SCHEMBL5306584 | 0.84 | NTRK1 (0.38) | HIF1AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL17844110 | 0.80 | MAOA (0.40) | GPR84MEN1KMT2APOLB | |
| SCHEMBL17844227 | 0.80 | POLB (0.39) | MEN1KMT2AHDAC1KDM4EALDH1A1 | |
| SCHEMBL3551960 | 0.78 | BRD4 (0.39) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL5261593 | 0.76 | MAPT (0.40) | TAAR1MEN1KMT2AF7F3 | |
| SCHEMBL5184298 | 0.76 | CA12 (0.33) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL17844141 | 0.75 | MEN1 (0.49) | MEN1KMT2ACASP3NPC1RAB9A | |
| SCHEMBL17844175 | 0.74 | CA12 (0.38) | MEN1KMT2AALDH1A1POLBGAA | |
| SCHEMBL17844236 | 0.73 | DRD2 (0.44) | MEN1KMT2ARAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |