Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | FYN | P06241 | 3/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844110 | 0.85 | MAOA (0.40) | POLBMEN1KMT2A | |
| SCHEMBL17844236 | 0.81 | DRD2 (0.44) | POLBLMNAKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL17844244 | 0.81 | MTNR1A (0.40) | LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL3551960 | 0.81 | BRD4 (0.39) | POLBRAD52MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL3653144 | 0.81 | SMN1; SMN2 (0.36) | SMN1; SMN2SYKCA12CA2CA9 | |
| SCHEMBL17844148 | 0.80 | KMT2A (0.40) | MAPTHTTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL17844130 | 0.80 | DRD2 (0.41) | LMNAMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL17844176 | 0.80 | ADORA3 (0.35) | AURKA | |
| SCHEMBL17844119 | 0.80 | TAAR1 (0.40) | POLBMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL17844228 | 0.79 | CYP1A2 (0.43) | LMNAMAPTHTTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |