Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20678598 | 0.80 | GABRA5 (0.49) | MAPTGABRA5 | |
| SCHEMBL17844243 | 0.80 | PRKAA2 (0.43) | GRIN1GRIN2BMAPTRECQLGABRA5 | |
| SCHEMBL3551960 | 0.79 | BRD4 (0.39) | MAPTRECQL | |
| SCHEMBL5184298 | 0.72 | CA12 (0.33) | MAPTKCNH2 | |
| SCHEMBL17844229 | 0.72 | MEN1 (0.48) | NPC1RAB9AMAPTRECQLMAPK1 | |
| SCHEMBL17844110 | 0.72 | MAOA (0.40) | — | |
| SCHEMBL17844227 | 0.71 | POLB (0.39) | MAPTSYKMAPK1 | |
| SCHEMBL17844175 | 0.71 | CA12 (0.38) | MAPTCYP2C19 | |
| SCHEMBL17844228 | 0.71 | CYP1A2 (0.43) | MAPTGABRA5GABRA1CYP1A2CYP2D6 | |
| SCHEMBL3653144 | 0.70 | SMN1; SMN2 (0.36) | KCNH2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |