Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | DRD4 | P21917 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844178 | 0.97 | DRD4 (0.43) | DRD2DRD4DRD3MAPTTAAR1 | |
| SCHEMBL17844247 | 0.92 | HTR1B (0.39) | DRD2DRD4DRD3MAPTL3MBTL1 | |
| SCHEMBL17844236 | 0.87 | DRD2 (0.44) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL17844180 | 0.87 | KDM4E (0.37) | MAPTRXFP1MEN1KMT2APOLB | |
| SCHEMBL17844246 | 0.86 | HCRTR1 (0.39) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL17844230 | 0.86 | DRD2 (0.46) | DRD2DRD4MAPTRXFP1MEN1 | |
| SCHEMBL5186747 | 0.86 | PTPN2 (0.37) | DRD2DRD4DRD3L3MBTL1POLB | |
| SCHEMBL5184327 | 0.85 | KDM4E (0.37) | L3MBTL1MEN1KMT2APOLBLMNA | |
| SCHEMBL17844130 | 0.82 | DRD2 (0.41) | DRD2DRD4DRD3MAPTL3MBTL1 | |
| SCHEMBL17844232 | 0.81 | DRD2 (0.44) | DRD2DRD4DRD3GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |