Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5186747 | 0.93 | PTPN2 (0.37) | HTR1BHTR1DGPR84MTNR1AMTNR1B | |
| SCHEMBL17844223 | 0.92 | DRD2 (0.41) | GPR84NPC1RAB9APOLBL3MBTL1 | |
| SCHEMBL17844178 | 0.89 | DRD4 (0.43) | GPR84POLBL3MBTL1MAPTDRD2 | |
| SCHEMBL17844246 | 0.89 | HCRTR1 (0.39) | NPC1RAB9APOLBSMN1; SMN2DRD2 | |
| SCHEMBL17844232 | 0.88 | DRD2 (0.44) | GPR84MTNR1AMTNR1BDRD2DRD4 | |
| SCHEMBL17844151 | 0.88 | PIM1 (0.39) | KDM4E | |
| SCHEMBL17844180 | 0.87 | KDM4E (0.37) | NPC1RAB9APOLBSMN1; SMN2MAPT | |
| SCHEMBL5184327 | 0.87 | KDM4E (0.37) | POLBL3MBTL1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL17844230 | 0.86 | DRD2 (0.46) | GPR84NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL17844169 | 0.86 | SCN9A (0.36) | GPR84POLBDRD2DRD4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |