Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 3/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844236 | 0.91 | DRD2 (0.44) | DRD2DRD4DRD3POLBRAB9A | |
| SCHEMBL17844178 | 0.90 | DRD4 (0.43) | DRD2DRD4DRD3POLBKDM4E | |
| SCHEMBL5186747 | 0.89 | PTPN2 (0.37) | DRD2DRD4DRD3POLBNPC1 | |
| SCHEMBL17844247 | 0.89 | HTR1B (0.39) | DRD2DRD4DRD3POLBNPC1 | |
| SCHEMBL17844169 | 0.89 | SCN9A (0.36) | HCRTR1HCRTR2DRD2DRD4POLB | |
| SCHEMBL17844180 | 0.88 | KDM4E (0.37) | POLBNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL5184340 | 0.88 | GBA1 (0.35) | KDM4EMEN1ALDH1A1HTTKMT2A | |
| SCHEMBL17844223 | 0.86 | DRD2 (0.41) | DRD2DRD4DRD3POLBNPC1 | |
| SCHEMBL17844232 | 0.84 | DRD2 (0.44) | DRD2DRD4DRD3KDM4EADRA1D | |
| SCHEMBL17844244 | 0.84 | MTNR1A (0.40) | NPC1KDM4EALDH1A1LMNAADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |