Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844212 | 0.92 | MTNR1A (0.42) | DRD2DRD4DRD3MTNR1AMTNR1B | |
| SCHEMBL17844169 | 0.90 | SCN9A (0.36) | DRD2DRD4KDM4EHDAC1HDAC2 | |
| SCHEMBL17844230 | 0.90 | DRD2 (0.46) | DRD2DRD4KDM4EHRH2GPR84 | |
| SCHEMBL5186747 | 0.88 | PTPN2 (0.37) | DRD2DRD4DRD3MTNR1AMTNR1B | |
| SCHEMBL17844247 | 0.88 | HTR1B (0.39) | DRD2DRD4DRD3MTNR1AMTNR1B | |
| SCHEMBL17844178 | 0.84 | DRD4 (0.43) | DRD2DRD4DRD3KDM4EGPR84 | |
| SCHEMBL17844246 | 0.84 | HCRTR1 (0.39) | DRD2DRD4ADRA1DADRA1AADRA1B | |
| SCHEMBL17844214 | 0.84 | CHRNB2 (0.44) | KDM4ECHRNB2CHRNA4 | |
| SCHEMBL5185121 | 0.83 | GPR84 (0.35) | GPR84 | |
| SCHEMBL17844180 | 0.83 | KDM4E (0.37) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |