Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844212 | 0.90 | MTNR1A (0.42) | DRD2DRD4KMT2AKDM4EPOLB | |
| SCHEMBL17844232 | 0.90 | DRD2 (0.44) | DRD2DRD4KDM4EGPR84HRH2 | |
| SCHEMBL17844178 | 0.89 | DRD4 (0.43) | DRD2DRD4KMT2AMAPTKDM4E | |
| SCHEMBL5186747 | 0.89 | PTPN2 (0.37) | DRD2DRD4GPR84POLBNPC1 | |
| SCHEMBL17844169 | 0.88 | SCN9A (0.36) | DRD2DRD4KMT2AKDM4EGPR84 | |
| SCHEMBL17844247 | 0.86 | HTR1B (0.39) | DRD2DRD4KMT2AMAPTKDM4E | |
| SCHEMBL17844223 | 0.86 | DRD2 (0.41) | DRD2DRD4KMT2AMAPTGPR84 | |
| SCHEMBL17844151 | 0.83 | PIM1 (0.39) | KDM4E | |
| SCHEMBL17844180 | 0.83 | KDM4E (0.37) | KMT2AMAPTKDM4EPOLBRXFP1 | |
| SCHEMBL17844246 | 0.83 | HCRTR1 (0.39) | DRD2DRD4KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |