Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HEXA | P06865 | 1/20 | 0.36 |
| ▸ | HEXB | P07686 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844130 | 0.88 | DRD2 (0.41) | NPSR1TSHRHPGDLMNAALDH1A1 | |
| SCHEMBL17844148 | 0.88 | KMT2A (0.40) | HPGDALDH1A1GAANPC1KDM4E | |
| SCHEMBL17844236 | 0.87 | DRD2 (0.44) | MTNR1AMTNR1BNPSR1LMNAHEXA | |
| SCHEMBL17844246 | 0.84 | HCRTR1 (0.39) | ADRA1DADRA1AADRA1BLMNAALDH1A1 | |
| SCHEMBL5186747 | 0.84 | PTPN2 (0.37) | MTNR1AMTNR1BNPC1L3MBTL1 | |
| SCHEMBL17844247 | 0.83 | HTR1B (0.39) | MTNR1AMTNR1BHPGDLMNAALDH1A1 | |
| SCHEMBL17844178 | 0.82 | DRD4 (0.43) | TSHRALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL17844176 | 0.82 | ADORA3 (0.35) | HTR1AADRA1DADRA1AADRA1BTSHR | |
| SCHEMBL17844227 | 0.81 | POLB (0.39) | HPGDLMNAALDH1A1KDM4E | |
| SCHEMBL17844180 | 0.81 | KDM4E (0.37) | LMNAALDH1A1GAANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |