SCHEMBL17844295

SCHEMBL17844295

CCCCCCCCCCCCCCCC(=O)NC(CCCCN)C(=O)NCC(=O)NC(Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ SLC6A5 Q9Y345 2/20 0.52
▸ ITGB3 P05106 2/20 0.49
▸ ITGA2B P08514 2/20 0.49
▸ TLR2 O60603 2/20 0.43
▸ NOD1 Q9Y239 4/20 0.43
▸ SIRT1 Q96EB6 2/20 0.41
▸ SIRT6 Q8N6T7 1/20 0.41
▸ NMT2 O60551 1/20 0.41
▸ NMT1 P30419 1/20 0.41
▸ GRIA1 P42261 1/20 0.41
▸ SIRT2 Q8IXJ6 1/20 0.41
▸ SIRT3 Q9NTG7 1/20 0.41
▸ FAAH O00519 2/20 0.41
▸ APLNR P35414 1/20 0.41
▸ GLP1R P43220 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17844297 1.00 SLC6A5 (0.52) SLC6A5ITGB3ITGA2BTLR2NOD1
SCHEMBL29467847 0.94 SLC6A5 (0.49) SLC6A5ITGB3ITGA2BTLR2NOD1
SCHEMBL1163474 0.90 SLC6A5 (0.52) SLC6A5ITGB3ITGA2BTLR2NOD1
SCHEMBL322731 0.90 SLC6A5 (0.52) SLC6A5ITGB3ITGA2BTLR2NOD1
SCHEMBL31138844 0.90 SLC6A5 (0.50) SLC6A5ITGB3ITGA2BTLR2NOD1
SCHEMBL30740007 0.89 APLNR (0.50) SLC6A5TLR2APLNRGLP1R
SCHEMBL31474897 0.89 APLNR (0.50) SLC6A5TLR2APLNRGLP1R
SCHEMBL30716920 0.87 SLC6A5 (0.52) SLC6A5ITGB3ITGA2BTLR2NOD1
SCHEMBL29941942 0.87 SLC6A5 (0.52) SLC6A5ITGB3ITGA2BTLR2NOD1
SCHEMBL29429317 0.86 SLC6A5 (0.48) SLC6A5ITGB3ITGA2BNOD1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311939-B Peptides, compositions comprising said peptides and uses thereof, in particular cosmetic uses 赛德玛公司 2022-10-04 — — CN disclosed
US-11001607-B2 Peptide, composition comprising said peptide and uses thereof, in particular cosmetic uses SEDERMA (FR) 2021-05-11 — — US disclosed
EP-3233210-B1 TRIPEPTIDES, COMPOSITIONS THEREOF AND THEIR COSMETIC USES SEDERMA SA (FR) 2020-02-05 — — EP disclosed
US-20190153030-A1 PEPTIDE, COMPOSITION COMPRISING SAID PEPTIDE AND USES THEREOF, IN PARTICULAR COSMETIC USES SEDERMA (FR) 2019-05-23 — — US disclosed
EP-3468983-A1 PEPTIDE, COMPOSITION COMPRISING SAID PEPTIDE AND USES THEREOF, IN PARTICULAR COSMETIC USES SEDERMA (FR) 2019-04-17 — — EP disclosed
WO-2017216177-A1 PEPTIDE, COMPOSITION COMPRISING SAID PEPTIDE AND USES THEREOF, IN PARTICULAR COSMETIC USES SEDERMA (FR) 2017-12-21 — — WO disclosed
EP-3233210-A1 TRIPEPTIDES, COMPOSITIONS THEREOF AND THEIR COSMETIC USES Sederma (FR) 2017-10-25 — — EP disclosed
WO-2016097966-A1 TRIPEPTIDES, COMPOSITIONS THEREOF AND THEIR COSMETIC USES SEDERMA (FR) 2016-06-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190153030-A1 PEPTIDE, COMPOSITION COMPRISING SAID PEPTIDE AND USES THEREOF, IN PARTICULAR COSMETIC USES PLOD3, CUTA, PLOD1 SLC6A5 3224/4885ITGB3 2647/4885ITGA2B 2654/4885
US-11001607-B2 Peptide, composition comprising said peptide and uses thereof, in particular cosmetic uses PLOD3, CUTA, PLOD1 SLC6A5 3224/4885ITGB3 2647/4885ITGA2B 2654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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