Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436790 | 0.83 | ADRA1D (0.58) | MAPK1GAAKDM4EDRD2HTR7 | |
| SCHEMBL2680583 | 0.82 | KDM4E (0.56) | MAPK1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL17861488 | 0.81 | ABCB1 (0.55) | MAPK1ALDH1A1KMT2AKDM4E | |
| SCHEMBL8285114 | 0.80 | USP2 (0.56) | MAPK1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8939993 | 0.80 | ALDH1A1 (0.64) | MAPK1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL17219336 | 0.80 | LMNA (0.58) | ALDH1A1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL7985824 | 0.78 | SLC18A3 (0.63) | MAPK1SMN1; SMN2 | |
| SCHEMBL19753773 | 0.78 | KMT2A (0.46) | MAPK1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL9400933 | 0.77 | HTR1A (0.63) | MAPK1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1275567 | 0.77 | HTR1A (0.68) | ALDH1A1DRD2DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233827-A1 | ANTIBACTERIAL COMPOUNDS HAVING BROAD SPECTRUM OF ACTIVITY | Aziende Chimiche Riunite Angelini Francesco A.C.R. (IT) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016096686-A1 | ANTIBACTERIAL COMPOUNDS HAVING BROAD SPECTRUM OF ACTIVITY | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2016-06-23 | — | — | WO | disclosed |