Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 12/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845386 | 0.86 | ROCK2 (0.36) | P2RX7 | |
| SCHEMBL17845569 | 0.80 | GAA (0.38) | LMNAKMT2AP2RX7TAS1R3TAS1R1 | |
| SCHEMBL17845530 | 0.79 | GAA (0.41) | EPHX2KMT2AALDH1A1P2RX7TAS1R3 | |
| SCHEMBL17845712 | 0.79 | KMT2A (0.33) | KMT2A | |
| SCHEMBL17845706 | 0.76 | RAB9A (0.40) | LMNAKMT2AALDH1A1P2RX7 | |
| SCHEMBL17845595 | 0.72 | DDB1 (0.43) | LMNAP2RX7 | |
| SCHEMBL17845726 | 0.72 | KMT2A (0.40) | KMT2AALDH1A1P2RX7TAS1R3TAS1R1 | |
| SCHEMBL17845534 | 0.71 | POLB (0.42) | LMNAKMT2AALDH1A1 | |
| SCHEMBL9847935 | 0.70 | EPHX2 (0.49) | EPHX2LMNAALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL17845720 | 0.70 | NPC1 (0.34) | LMNAKMT2AALDH1A1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |