Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845726 | 0.87 | KMT2A (0.40) | KMT2AP2RX7MAPT | |
| SCHEMBL17845386 | 0.78 | ROCK2 (0.36) | P2RX7OPRL1 | |
| SCHEMBL17845502 | 0.77 | MAPT (0.47) | MEN1KMT2AMAPK14TSHRLMNA | |
| SCHEMBL17845720 | 0.77 | NPC1 (0.34) | MEN1KMT2AP2RX7CXCR2LMNA | |
| SCHEMBL17845530 | 0.77 | GAA (0.41) | MEN1KMT2AP2RX7TSHR | |
| SCHEMBL17845706 | 0.74 | RAB9A (0.40) | MEN1KMT2AP2RX7MAPK14LMNA | |
| SCHEMBL17845787 | 0.74 | MAPT (0.40) | KMT2ATSHRLMNAMAPT | |
| SCHEMBL17845380 | 0.73 | DDB1 (0.40) | MAPT | |
| SCHEMBL17845348 | 0.71 | FADS1 (0.52) | MEN1KMT2ATSHRLMNAMAPT | |
| SCHEMBL17845762 | 0.70 | EPHX2 (0.36) | KMT2AP2RX7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |