Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.36 |
| ▸ | GLRB | P48167 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845714 | 0.83 | SMN1; SMN2 (0.38) | TAS1R3TAS1R1SMN1; SMN2ALOX15TSHR | |
| SCHEMBL17845715 | 0.83 | SMN1; SMN2 (0.38) | TAS1R3TAS1R1SMN1; SMN2ALOX15TSHR | |
| SCHEMBL17845533 | 0.83 | KMT2A (0.42) | SMN1; SMN2TSHRMAPTLMNANPSR1 | |
| SCHEMBL17845710 | 0.80 | EPHX2 (0.38) | TAS1R3TAS1R1SMN1; SMN2NPSR1POLB | |
| SCHEMBL17845581 | 0.76 | RAB9A (0.43) | SMN1; SMN2MAPTLMNAPOLBNPC1 | |
| SCHEMBL1645759 | 0.70 | DRD2 (0.52) | SMN1; SMN2ALOX15TSHRMAPTLMNA | |
| SCHEMBL21400554 | 0.69 | TAS1R3 (0.64) | TAS1R3TAS1R1SMN1; SMN2ALOX15TSHR | |
| SCHEMBL17845784 | 0.69 | SMN1; SMN2 (0.40) | SMN1; SMN2ALOX15TSHRMAPTLMNA | |
| SCHEMBL17384347 | 0.68 | TAS1R3 (0.49) | TAS1R3TAS1R1SMN1; SMN2ALOX15TSHR | |
| SCHEMBL17845550 | 0.68 | SYK (0.38) | SMN1; SMN2LMNANPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |