Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845641 | 0.85 | LMNA (0.40) | KMT2AMEN1NPSR1LMNAKDM4E | |
| SCHEMBL17845593 | 0.83 | TAS1R3 (0.40) | NPSR1LMNAGAAMAPTPOLB | |
| SCHEMBL17845587 | 0.80 | GAA (0.39) | NPSR1KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL17845581 | 0.78 | RAB9A (0.43) | KMT2AMEN1LMNAMAPTL3MBTL1 | |
| SCHEMBL17845485 | 0.69 | GAA (0.42) | KMT2AMEN1NPSR1LMNAKDM4E | |
| SCHEMBL17845582 | 0.67 | KMT2A (0.42) | KMT2AMEN1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL17845715 | 0.67 | SMN1; SMN2 (0.38) | KMT2ANPSR1LMNAKDM4EGAA | |
| SCHEMBL17845714 | 0.67 | SMN1; SMN2 (0.38) | NPSR1LMNAGAAMAPTL3MBTL1 | |
| SCHEMBL17845600 | 0.65 | ALDH1A1 (0.40) | LMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL17845550 | 0.65 | SYK (0.38) | KMT2AMEN1LMNAKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |