Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.64 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17384347 | 0.79 | TAS1R3 (0.49) | TAS1R3TAS1R1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL701072 | 0.79 | TAS1R3 (1.00) | TAS1R3TAS1R1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL19915073 | 0.78 | NPSR1 (0.61) | LMNANPSR1SMN1; SMN2TSHRALOX15 | |
| SCHEMBL21239457 | 0.78 | TAS1R3 (0.47) | TAS1R3TAS1R1KDM4EALDH1A1HTT | |
| SCHEMBL1646836 | 0.76 | LMNA (0.55) | LMNANPSR1SMN1; SMN2TSHRALOX15 | |
| SCHEMBL1645759 | 0.75 | DRD2 (0.52) | LMNANPSR1SMN1; SMN2TSHRALOX15 | |
| SCHEMBL21400405 | 0.75 | HTT (0.49) | TAS1R3TAS1R1LMNAALDH1A1HTT | |
| SCHEMBL9753902 | 0.73 | TACR1 (0.65) | — | |
| SCHEMBL7634555 | 0.72 | ALDH1A1 (0.51) | TAS1R3TAS1R1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL4958849 | 0.71 | CHRNA7 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3760620-A1 | RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USAGE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2021-01-06 | — | — | EP | disclosed |
| WO-2019179515-A1 | RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 北京泰德制药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |