Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845543 | 0.84 | DDB1 (0.39) | KDM4EMEN1KMT2AGAAMAPT | |
| SCHEMBL17845686 | 0.84 | FADS1 (0.43) | MEN1KMT2ARAB9ANPC1IDO1 | |
| SCHEMBL17845628 | 0.84 | KDM4E (0.42) | KDM4ETRPA1MEN1KMT2ARAB9A | |
| SCHEMBL17845655 | 0.83 | TSHR (0.37) | MEN1KMT2ANPC1EPHX2MAPT | |
| SCHEMBL17845763 | 0.83 | KDM4E (0.41) | KDM4ETRPA1MEN1KMT2ARAB9A | |
| SCHEMBL17845696 | 0.82 | DDB1 (0.35) | TRPA1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL17845760 | 0.82 | ALDH1A1 (0.40) | GAASMN1; SMN2 | |
| SCHEMBL17845537 | 0.80 | RAB9A (0.43) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17845768 | 0.77 | HTT (0.38) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL17845599 | 0.74 | MEN1 (0.33) | MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |