Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845537 | 0.86 | RAB9A (0.43) | HTTSMN1; SMN2ROCK2RAB9ANPC1 | |
| SCHEMBL17845550 | 0.85 | SYK (0.38) | HTTHSD17B10SMN1; SMN2ROCK2RAB9A | |
| SCHEMBL17845686 | 0.78 | FADS1 (0.43) | HTTRAB9ACYP3A4NPC1ALDH1A1 | |
| SCHEMBL17845543 | 0.78 | DDB1 (0.39) | HTTCYP3A4ALDH1A1KDM4EKMT2A | |
| SCHEMBL17845596 | 0.77 | KDM4E (0.41) | HTTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL17845760 | 0.75 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL17845449 | 0.72 | ROCK2 (0.42) | HTTHSD17B10SMN1; SMN2ROCK2RAB9A | |
| SCHEMBL17845612 | 0.72 | HPGD (0.38) | HTTSMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL17845581 | 0.71 | RAB9A (0.43) | HTTSMN1; SMN2ROCK2RAB9ANPC1 | |
| SCHEMBL17845540 | 0.71 | RAB9A (0.43) | HTTHSD17B10SMN1; SMN2ROCK2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |