Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845579 | 0.77 | DDB1 (0.35) | ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL17845711 | 0.77 | ALDH1A1 (0.35) | ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL17845590 | 0.77 | SMN1; SMN2 (0.40) | ALDH1A1LMNASMN1; SMN2RAB9AGAA | |
| SCHEMBL17845717 | 0.77 | MAPK1 (0.39) | ALDH1A1HTTKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL17845669 | 0.76 | ALDH1A1 (0.40) | ALDH1A1LMNASMN1; SMN2GAAGFER | |
| SCHEMBL17845643 | 0.75 | KMT2A (0.37) | ALDH1A1LMNANPC1MEN1KMT2A | |
| SCHEMBL17845763 | 0.75 | KDM4E (0.41) | KDM4ESMN1; SMN2RAB9AGAANPC1 | |
| SCHEMBL17845626 | 0.75 | FADS1 (0.42) | ALDH1A1HTTLMNARAB9AGAA | |
| SCHEMBL17845540 | 0.75 | RAB9A (0.43) | ALDH1A1HTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL15830050 | 0.69 | BACE1 (0.44) | ALDH1A1HTTKDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |