Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CCR6 | P51684 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | MERTK | Q12866 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13450514 | 0.92 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTNPC1RAB9A | |
| SCHEMBL3108892 | 0.92 | RAB9A (0.57) | ALDH1A1GAAMAPTNPC1RAB9A | |
| SCHEMBL7790492 | 0.91 | ALDH1A1 (0.52) | ALDH1A1GAAMAPTNPC1RAB9A | |
| SCHEMBL674674 | 0.90 | RAB9A (0.59) | ALDH1A1GAAMAPTNPC1RAB9A | |
| SCHEMBL3121134 | 0.87 | ALDH1A1 (0.49) | ALDH1A1GAAMAPTNPC1RAB9A | |
| SCHEMBL4140224 | 0.87 | HTR6 (0.57) | ALDH1A1GAAMAPTNPC1RAB9A | |
| SCHEMBL31152659 | 0.85 | POLB (0.65) | ALDH1A1GAAMAPTKDM4ENPSR1 | |
| SCHEMBL9822760 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPTNPC1RAB9ATDP1 | |
| SCHEMBL24538113 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MAPTNPC1RAB9AMAPK1 | |
| SCHEMBL24537639 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MAPTNPC1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |
| CN-112898173-B | Method for preparing amide compound by photocatalytic organic amine | 湖南中医药大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-109153636-B | Cyclopropyl-amide compounds as dual LSD1/HDAC inhibitors | 朱比连特埃皮科尔有限责任公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-112898173-A | Method for preparing amide compound by photocatalytic organic amine | 湖南中医药大学 | 2021-06-04 | — | — | CN | disclosed |
| WO-2019016385-A1 | BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2019-01-24 | — | — | WO | disclosed |
| CN-109153636-A | Cyclopropyl-amide compound as dual LSD1/HDAC inhibitor | 朱比连特比利斯有限公司 | 2019-01-04 | — | — | CN | disclosed |
| US-8741934-B2 | Inhibitors of ion channels | PFIZER LIMITED (GB) | 2014-06-03 | — | — | US | disclosed |
| CN-102863341-B | Chemical synthesis method of (1R, 2S)-2-aryl cyclopropylamine derivative | UNIV NANTONG | 2014-05-07 | — | — | CN | disclosed |
| US-20130072471-A1 | Inhibitors of Ion Channels | MARRON BRIAN EDWARD (US) | 2013-03-21 | — | — | US | disclosed |
| EP-2560978-A1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | Mars, Incorporated (US) | 2013-02-27 | — | — | EP | disclosed |
| US-8357711-B2 | Heterocyclic sulfonamides as inhibitors of ion channels | PFIZER LIMITED (GB) | 2013-01-22 | — | — | US | disclosed |
| CN-102863341-A | Chemical synthesis method of (1R, 2S)-2-aryl cyclopropylamine derivative | UNIV NANTONG | 2013-01-09 | — | — | CN | disclosed |
| WO-2011133653-A1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | MARS, INCORPORATED (US) | 2011-10-27 | — | — | WO | disclosed |
| US-20090143358-A1 | INHIBITORS OF ION CHANNELS | ICAGEN, INC. (US) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072471-A1 | Inhibitors of Ion Channels | TRPV1, TRPV5, TRPA1 | ALDH1A1 3113/4885GAA 3679/4885MAPT 2938/4885 |
| US-20090143358-A1 | INHIBITORS OF ION CHANNELS | TRPV1, TRPV5, TRPA1 | ALDH1A1 3113/4885GAA 3679/4885MAPT 2938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.