SCHEMBL17845703

SCHEMBL17845703

Oc1ccc(O)c(NC2CCO[C]2Cl)c1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
CCR6 P51684 1/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17845510 0.82 ESR1 (0.32) ESR1ESR2MAOAMAOB
SCHEMBL17845720 0.81 NPC1 (0.34) CCR6
SCHEMBL17845598 0.78 ALDH1A1 (0.36) ESR2
SCHEMBL17845578 0.76 TSHR (0.39) MAOB
SCHEMBL17845706 0.72 RAB9A (0.40)
SCHEMBL17845726 0.71 KMT2A (0.40)
SCHEMBL17845530 0.69 GAA (0.41)
SCHEMBL17845502 0.69 MAPT (0.47)
SCHEMBL17845453 0.69 MEN1 (0.41)
SCHEMBL17845762 0.68 EPHX2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3233860-A1 SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS Univerzita Palackého V Olomouci (CZ) 2017-10-25 EP disclosed
WO-2016095881-A1 SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2016-06-23 WO disclosed