Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 9/20 | 0.67 |
| ▸ | GSK3A | P49840 | 2/20 | 0.62 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.62 |
| ▸ | NT5E | P21589 | 1/20 | 0.61 |
| ▸ | PNP | P00491 | 1/20 | 0.57 |
| ▸ | TGM2 | P21980 | 1/20 | 0.57 |
| ▸ | KRAS | P01116 | 2/20 | 0.54 |
| ▸ | TYMP | P19971 | 1/20 | 0.53 |
| ▸ | PDE2A | O00408 | 1/20 | 0.53 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1533274 | 0.95 | HINT1 (0.73) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL26622676 | 0.85 | HINT1 (0.62) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL16163344 | 0.83 | HINT1 (0.70) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL1138984 | 0.83 | HINT1 (0.75) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL2335177 | 0.83 | HINT1 (0.69) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL4963673 | 0.83 | HINT1 (0.60) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL26212718 | 0.82 | HINT1 (0.59) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL439016 | 0.82 | HINT1 (0.78) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL6826563 | 0.82 | HINT1 (0.68) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL5219707 | 0.82 | GSK3A (0.80) | HINT1GSK3ARPS6KA3MAPK14NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233880-A1 | END CAPPED NUCLEIC ACID MOLECULES | Novartis AG (CH) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016098028-A1 | END CAPPED NUCLEIC ACID MOLECULES | NOVARTIS AG (CH) | 2016-06-23 | — | — | WO | disclosed |