SCHEMBL26622676

SCHEMBL26622676

Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](COCc3ccccc3)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HINT1 P49773 6/20 0.62
GSK3A P49840 2/20 0.55
RPS6KA3 P51812 2/20 0.55
MAPK14 Q16539 2/20 0.55
ADORA2A P29274 3/20 0.55
ADORA2B P29275 3/20 0.55
NT5E P21589 1/20 0.54
HPGD P15428 2/20 0.52
PDE2A O00408 1/20 0.51
PNP P00491 1/20 0.51
TGM2 P21980 1/20 0.51
TAAR1 Q96RJ0 1/20 0.51
ADORA3 P0DMS8 2/20 0.49
ADORA1 P30542 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26208037 0.92 HINT1 (0.58) HINT1GSK3ARPS6KA3MAPK14ADORA2A
SCHEMBL1533274 0.90 HINT1 (0.73) HINT1GSK3ARPS6KA3MAPK14ADORA2A
SCHEMBL26622675 0.90 NT5E (0.61) HINT1GSK3ARPS6KA3MAPK14NT5E
SCHEMBL26212718 0.89 HINT1 (0.59) HINT1GSK3ARPS6KA3MAPK14NT5E
SCHEMBL26808396 0.87 HINT1 (0.60) HINT1GSK3ARPS6KA3MAPK14ADORA2A
SCHEMBL26808259 0.87 HINT1 (0.60) HINT1GSK3ARPS6KA3MAPK14ADORA2A
SCHEMBL26622682 0.87 TGM2 (0.62) HINT1NT5ETGM2
SCHEMBL26622652 0.87 HINT1 (0.63) HINT1GSK3ARPS6KA3MAPK14ADORA2A
SCHEMBL31516979 0.86 HINT1 (0.62) HINT1GSK3ARPS6KA3MAPK14ADORA2A
SCHEMBL31516974 0.86 HINT1 (0.62) HINT1GSK3ARPS6KA3MAPK14ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF GUANGZHOU HENOVCOM BIOSCIENCE CO., LTD. (CN) 2023-10-26 US disclosed
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF GUANGZHOU HENOVCOM BIOSCIENCE CO., LTD. (CN) 2023-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF RNGTT, RNMT, NSUN2 HINT1 706/4885GSK3A 4107/4885RPS6KA3 659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.