SCHEMBL26212718

SCHEMBL26212718

C[C@H]1OC(n2cnc3c(=O)[nH]c(N)nc32)[C@H](O)[C@@H]1COCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HINT1 P49773 6/20 0.59
TAAR1 Q96RJ0 2/20 0.53
GSK3A P49840 2/20 0.52
RPS6KA3 P51812 2/20 0.52
MAPK14 Q16539 2/20 0.52
NT5E P21589 1/20 0.51
PNP P00491 2/20 0.48
PDE2A O00408 1/20 0.48
TGM2 P21980 1/20 0.47
TAS1R3 Q7RTX0 1/20 0.47
TAS1R1 Q7RTX1 1/20 0.47
FUT5 Q11128 1/20 0.47
STING1 Q86WV6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26622676 0.89 HINT1 (0.62) HINT1TAAR1GSK3ARPS6KA3MAPK14
SCHEMBL1533274 0.87 HINT1 (0.73) HINT1TAAR1GSK3ARPS6KA3MAPK14
SCHEMBL26205426 0.85 HINT1 (0.59) HINT1TAAR1GSK3ARPS6KA3MAPK14
SCHEMBL26622675 0.85 NT5E (0.61) HINT1GSK3ARPS6KA3MAPK14NT5E
SCHEMBL26568476 0.83 HINT1 (0.41) HINT1TAAR1GSK3ARPS6KA3MAPK14
SCHEMBL26622682 0.83 TGM2 (0.62) HINT1NT5ETGM2TAS1R3TAS1R1
SCHEMBL26208037 0.82 HINT1 (0.58) HINT1TAAR1GSK3ARPS6KA3MAPK14
SCHEMBL17845832 0.82 HINT1 (0.67) HINT1TAAR1GSK3ARPS6KA3MAPK14
SCHEMBL26201877 0.81 HINT1 (0.55) HINT1TAAR1GSK3ARPS6KA3MAPK14
SCHEMBL26202544 0.80 HINT1 (0.55) HINT1TAAR1GSK3ARPS6KA3MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023159930-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND 广州市恒诺康医药科技有限公司 2023-08-31 WO disclosed