SCHEMBL727904

SCHEMBL727904

CNc1ccc(O)c(C(=O)O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 3/20 0.57
CSNK2A1 P68400 1/20 0.57
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
PTGS2 P35354 2/20 0.55
CA12 O43570 1/20 0.55
ALOX5 P09917 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55
KLKB1 P03952 1/20 0.55
CTSB P07858 1/20 0.55
MMP9 P14780 1/20 0.55
DNMT1 P26358 1/20 0.55
DNMT3B Q9UBC3 1/20 0.55
DNMT3L Q9UJW3 1/20 0.55
DNMT3A Q9Y6K1 1/20 0.55
MAPT P10636 3/20 0.53
ALDH1A1 P00352 3/20 0.53
TDP1 Q9NUW8 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroquinone SCHEMBL28816725 0.94 CA1 (0.60) KDM4CCSNK2A1CA1CA2PTGS2
SCHEMBL4582016 0.93 PTPN1 (0.51) KDM4CCSNK2A1CA1CA2PTGS2
SCHEMBL730081 0.84 KMT2A (0.57) CA1CA2CA12CA7CA9
SCHEMBL12904426 0.84 P2RX1 (0.43) KDM4CCA1CA2CA12CA7
SCHEMBL2130340 0.83 CA1 (0.59) KDM4CCSNK2A1CA1CA2PTGS2
SCHEMBL18331069 0.83 CA1 (0.59) KDM4CCSNK2A1CA1CA2PTGS2
SCHEMBL709947 0.83 HSD17B10 (0.47) KDM4CMAPTALDH1A1TDP1KDM4E
SCHEMBL17118247 0.82 F3 (0.44) KDM4CCSNK2A1MAPTALDH1A1TDP1
SCHEMBL170522 0.81 KDM4C (0.62) KDM4CCSNK2A1CA1CA2PTGS2
SCHEMBL30076649 0.81 KDM4C (0.62) KDM4CCSNK2A1CA1CA2PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116063472-A anti-Spike S2 protein antibody and application thereof 江苏东抗生物医药科技有限公司 2023-05-05 CN claimed
US-20180064667-A1 METHODS OF TREATING LACTOSE INTOLERANCE NOGRA PHARMA LTD (IE) 2018-03-08 US claimed
CN-104284655-A Methods of treating lactose intolerance NOGRA PHARMA LTD 2015-01-14 CN claimed
US-20110152225-A1 PPAR-Gamma Agonists for the Induction of Cationic Antimicrobial Peptide Expression as Immunoprotective Stimulants NOGRA PHARMA LIMITED (IE) 2011-06-23 US claimed
EP-2131829-A1 PPAR-GAMMA AGONISTS FOR THE INDUCTION OF CATIONIC ANTIMICROBIAL PEPTIDE EXPRESSION AS IMMUNOPROTECTIVE STIMULANTS Giuliani International Limited (IE) 2009-12-16 EP claimed
US-20090118357-A1 Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field GIULIANI INTERNATIONAL LIMITED (IE) 2009-05-07 US claimed
WO-2008104557-A1 PPAR-GAMMA AGONISTS FOR THE INDUCTION OF CATIONIC ANTIMICROBIAL PEPTIDE EXPRESSION AS IMMUNOPROTECTIVE STIMULANTS GIULIANI INTERNATIONAL LIMITED (IE) 2008-09-04 WO claimed
US-12291494-B2 Methods of treating fibrosis NOGRA PHARMA LIMITED (IE) 2025-05-06 US disclosed
CN-119613524-A Polypeptide for inhibiting and reversing pathological aggregation of human lens protein gamma D 中国医学科学院基础医学研究所 2025-03-14 CN disclosed
US-20240279157-A1 METHODS OF TREATING FIBROSIS NOGRA PHARMA LIMITED (IE) 2024-08-22 US disclosed
US-20240076315-A1 KHL POLYPEPTIDE, AND USE THEREOF IN PREPARATION OF TABP-EIC CELL ALLIFE MEDICINE (ZHUHAI) LIMITED (CN) 2024-03-07 US disclosed
CN-110612447-B Assays for detecting early pancreatic cancer 德克萨斯州立大学董事会 2024-02-06 CN disclosed
CN-113667740-B Use of molecular marker combinations in diagnosing cardiovascular diseases 河北医科大学第二医院 2023-12-26 CN disclosed
US-20090118357-A1 Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field GIULIANI INTERNATIONAL LIMITED (IE) 2009-05-07 US disclosed
US-20090118357-A1 Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field GIULIANI INTERNATIONAL LIMITED (IE) 2009-05-07 US disclosed
US-20090118357-A1 Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field GIULIANI INTERNATIONAL LIMITED (IE) 2009-05-07 US disclosed
WO-2008104557-A1 PPAR-GAMMA AGONISTS FOR THE INDUCTION OF CATIONIC ANTIMICROBIAL PEPTIDE EXPRESSION AS IMMUNOPROTECTIVE STIMULANTS GIULIANI INTERNATIONAL LIMITED (IE) 2008-09-04 WO disclosed
EP-1910275-A2 COMPOUNDS AND THEIR SALTS SPECIFIC TO THE PPAR RECEPTORS AND THE EGF RECEPTORS AND THEIR USE IN THE MEDICAL FIELD Giuliani International Limited (IE) 2008-04-16 EP disclosed
WO-2007010514-A2 COMPOUNDS AND THEIR SALTS SPECIFIC TO THE PPAR RECEPTORS AND THE EGF RECEPTORS AND THEIR USE IN THE MEDICAL FIELD GIULIANI INTERNATIONAL LIMITED (IE) 2007-01-25 WO disclosed
WO-2007010514-A2 COMPOUNDS AND THEIR SALTS SPECIFIC TO THE PPAR RECEPTORS AND THE EGF RECEPTORS AND THEIR USE IN THE MEDICAL FIELD GIULIANI INTERNATIONAL LIMITED (IE) 2007-01-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090118357-A1 Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field EGFR, ERBB3, FGFR3 KDM4C 4462/4885CSNK2A1 871/4885CA1 4260/4885
US-20240279157-A1 METHODS OF TREATING FIBROSIS MMP1, MMP8, FABP2 KDM4C 2264/4885CSNK2A1 2797/4885CA1 4002/4885
US-12291494-B2 Methods of treating fibrosis MMP1, MMP8, FABP2 KDM4C 2264/4885CSNK2A1 2797/4885CA1 4002/4885
US-20180064667-A1 METHODS OF TREATING LACTOSE INTOLERANCE LCT, LPL, PPARG KDM4C 3909/4885CSNK2A1 655/4885CA1 3821/4885
US-20110152225-A1 PPAR-Gamma Agonists for the Induction of Cationic Antimicrobial Peptide Expression as Immunoprotective Stimulants PPARG, FABP2, PPARD KDM4C 4838/4885CSNK2A1 3820/4885CA1 4514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.