Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.59 |
| ▸ | METAP2 | P50579 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16187952 | 0.83 | UQCRB (0.60) | ACLYKEAP1NFE2L2MAPTMAPK1 | |
| SCHEMBL3075935 | 0.82 | METAP2 (0.57) | METAP2CA2CA9KEAP1NFE2L2 | |
| SCHEMBL31681419 | 0.82 | CA2 (0.60) | METAP2LMNACA12CA2CA9 | |
| SCHEMBL17849571 | 0.82 | KAT6A (0.59) | METAP2KEAP1NFE2L2MAPTMEN1 | |
| SCHEMBL17849556 | 0.80 | HSD17B2 (0.71) | LMNACA2ALDH1A1CA1KDM4E | |
| SCHEMBL17849558 | 0.80 | MAPT (0.64) | METAP2LMNACA12CA2CA9 | |
| SCHEMBL3072539 | 0.79 | LMNA (0.70) | LMNACA12CA2CA9MCOLN3 | |
| SCHEMBL28407595 | 0.78 | LMNA (0.70) | METAP2LMNACA12CA2CA9 | |
| SCHEMBL19050676 | 0.78 | METAP2 (0.55) | METAP2KEAP1NFE2L2GAAHTT | |
| SCHEMBL13667266 | 0.77 | APP (0.55) | METAP2LMNAMAPTMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371286-B2 | Pharmaceutical composition with enhanced efficacy for inhibiting angiogenesis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-21 | — | — | US | disclosed |