SCHEMBL17849709

SCHEMBL17849709

CC1(C)c2cccc3ccc4cc(-c5cccc6c(Br)cccc56)cc1c4c23

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TYMS P04818 3/20 0.34
DHFR P00374 2/20 0.32
CYP1A2 P05177 2/20 0.31
ERBB2 P04626 1/20 0.31
FYN P06241 1/20 0.31
MAOA P21397 1/20 0.31
ACHE P22303 1/20 0.31
AHR P35869 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17849702 0.93 CYP1A2 (0.35) TYMSDHFRCYP1A2ERBB2FYN
SCHEMBL15909679 0.82 LPL (0.38) CYP1A2
SCHEMBL17849708 0.79 CYP1A2 (0.37) TYMSDHFRCYP1A2ERBB2FYN
SCHEMBL17849698 0.77 MAOB (0.34) TYMSMAOA
SCHEMBL13888836 0.77 MAOB (0.34) TYMSMAOA
SCHEMBL17849671 0.75 PDK2 (0.30)
SCHEMBL17849694 0.75 CYP2A6 (0.41) MAOANPSR1
SCHEMBL12982875 0.75 NPSR1 (0.40) TYMSDHFRCYP1A2ERBB2FYN
SCHEMBL31591206 0.75 MEN1 (0.34) TYMSDHFRCYP1A2ERBB2FYN
SCHEMBL12256088 0.75 MEN1 (0.34) TYMSDHFRCYP1A2ERBB2FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed