SCHEMBL17849702

SCHEMBL17849702

CC1(C)c2cccc3ccc4cc(-c5ccc(Br)c6ccccc56)cc1c4c23

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.35
ERBB2 P04626 1/20 0.33
FYN P06241 1/20 0.33
MAOA P21397 1/20 0.33
ACHE P22303 1/20 0.33
AHR P35869 1/20 0.33
ALDH1A1 P00352 1/20 0.32
THRB P10828 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
DHFR P00374 2/20 0.31
TYMS P04818 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
CYP1B1 Q16678 1/20 0.30
CES1 P23141 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17849709 0.93 TYMS (0.34) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL15909679 0.88 LPL (0.38) CYP1A2CYP2D6CYP2C19
SCHEMBL17849708 0.83 CYP1A2 (0.37) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL15731070 0.83 CYP1A2 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL16604200 0.77 CYP1A2 (0.45) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL17849671 0.77 PDK2 (0.30)
SCHEMBL17849651 0.77 RXRA (0.31)
SCHEMBL17849698 0.76 MAOB (0.34) MAOAALDH1A1TYMSMAPK1
SCHEMBL13888836 0.76 MAOB (0.34) MAOAALDH1A1TYMSMAPK1
SCHEMBL17849654 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed