Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | MPO | P05164 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7171815 | 0.81 | KDM4E (0.57) | P2RX7ALDH1A1KDM4EGFERMPO | |
| SCHEMBL30201887 | 0.81 | KDR (0.47) | ALDH1A1KDM4ECYP3A4PMP22CYP1A2 | |
| SCHEMBL27212647 | 0.81 | P2RX7 (0.50) | P2RX7ALDH1A1KDM4EMPOCYP3A4 | |
| SCHEMBL3257638 | 0.81 | KDR (0.47) | ALDH1A1KDM4ECYP3A4PMP22CYP1A2 | |
| SCHEMBL31345733 | 0.81 | P2RX7 (0.50) | P2RX7ALDH1A1KDM4EMPOCYP3A4 | |
| SCHEMBL31213280 | 0.79 | P2RX7 (0.49) | P2RX7KDM4EMPOCYP3A4CYP1A2 | |
| SCHEMBL1505656 | 0.79 | ALDH1A1 (0.61) | P2RX7ALDH1A1KDM4EMPOCYP3A4 | |
| SCHEMBL107759 | 0.79 | CTSA (0.50) | P2RX7KDM4E | |
| SCHEMBL29679606 | 0.79 | ALDH1A1 (0.61) | P2RX7ALDH1A1KDM4EMPOCYP3A4 | |
| SCHEMBL1054692 | 0.79 | KDM4C (0.58) | P2RX7ALDH1A1KDM4ECYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240317978-A1 | RUBBER COMPOSITION AND TIRE | OTSUKA CHEMICAL CO., LTD. (JP) | 2024-09-26 | — | — | US | disclosed |
| EP-4365229-A1 | RUBBER COMPOSITION AND TIRE | Otsuka Chemical Co., Ltd. (JP) | 2024-05-08 | — | — | EP | disclosed |
| CN-117561303-A | Rubber composition and tire | 大塚化学株式会社 | 2024-02-13 | — | — | CN | disclosed |
| EP-2424869-B1 | 5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-a]PYRAZINE DERIVATIVES AS P2X7 MODULATORS | GLAXO GROUP LTD (GB) | 2016-06-22 | — | — | EP | disclosed |