Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17882031 | 0.83 | HCAR2 (0.36) | ABCB11LMNACYP1A2CHRM2CHRM4 | |
| SCHEMBL17860704 | 0.80 | ALDH1A1 (0.48) | LMNATSHR | |
| SCHEMBL2295307 | 0.79 | ALDH1A1 (0.42) | LMNATSHRKCNH2HSD17B10 | |
| SCHEMBL17878583 | 0.77 | CA12 (0.37) | LMNAHSD17B10 | |
| SCHEMBL4613658 | 0.76 | NR1H2 (0.36) | LMNATSHRSIGMAR1 | |
| SCHEMBL2172060 | 0.75 | ALOX15 (0.31) | — | |
| SCHEMBL31050190 | 0.74 | CYP3A4 (0.39) | ABCB11LMNACYP1A2CHRM2CHRM4 | |
| SCHEMBL7548982 | 0.73 | CHRM2 (0.38) | ABCB11LMNACYP1A2CHRM2CHRM4 | |
| SCHEMBL17860867 | 0.73 | ALDH1A1 (0.45) | LMNATSHR | |
| SCHEMBL11303514 | 0.73 | CYP4F2 (0.41) | ABCB11LMNACYP1A2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100578-A2 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |