Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.30 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17882031 | 0.79 | HCAR2 (0.36) | MEN1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL27902213 | 0.77 | NR1H2 (0.36) | NR1H2NR1H3TSHRALDH1A1 | |
| SCHEMBL17860719 | 0.76 | ABCB11 (0.30) | TSHRLMNASIGMAR1 | |
| SCHEMBL17860704 | 0.76 | ALDH1A1 (0.48) | TSHRHPGDALDH1A1LMNA | |
| SCHEMBL4541788 | 0.75 | MEN1 (0.42) | MEN1KMT2ALMNA | |
| SCHEMBL2295307 | 0.74 | ALDH1A1 (0.42) | MEN1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL181358 | 0.73 | CYP4F2 (0.30) | TSHRALDH1A1 | |
| SCHEMBL28804992 | 0.73 | NR1H2 (0.34) | NR1H2NR1H3ALDH1A1 | |
| SCHEMBL17878583 | 0.73 | CA12 (0.37) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2172060 | 0.71 | ALOX15 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910404-A1 | HCV NS3 PROTEASE INHIBITORS | Merck & Co., Inc. (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007015855-A1 | HCV NS3 PROTEASE INHIBITORS | MERCK & CO., INC. (US) | 2007-02-08 | — | — | WO | disclosed |