Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 6/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.43 |
| ▸ | CTSG | P08311 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.41 |
| ▸ | ITGAV | P06756 | 2/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115938 | 0.91 | ABCB1 (0.45) | ABCB1BDKRB2ALDH1A1NPSR1TP53 | |
| SCHEMBL3400542 | 0.91 | ABCB1 (0.45) | ABCB1BDKRB2ALDH1A1NPSR1TP53 | |
| SCHEMBL3402980 | 0.88 | ALDH1A1 (0.44) | BDKRB2ELANEF2CTSGALDH1A1 | |
| SCHEMBL115758 | 0.88 | ALDH1A1 (0.44) | BDKRB2ELANEF2CTSGALDH1A1 | |
| SCHEMBL116032 | 0.88 | BDKRB2 (0.47) | ABCB1BDKRB2ALDH1A1NPSR1TP53 | |
| SCHEMBL13625881 | 0.87 | BDKRB2 (0.52) | ABCB1BDKRB2 | |
| SCHEMBL116901 | 0.86 | BDKRB2 (0.46) | ABCB1BDKRB2ALDH1A1NPSR1TP53 | |
| SCHEMBL114544 | 0.85 | BDKRB2 (0.45) | ABCB1BDKRB2ALDH1A1NPSR1TP53 | |
| SCHEMBL26893928 | 0.85 | ABCB1 (0.47) | ABCB1BDKRB2ALDH1A1TP53 | |
| SCHEMBL3398953 | 0.84 | ALDH1A1 (0.46) | BDKRB2ALDH1A1NPSR1TP53P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | RECQL, BLVRB, NQO2 | ABCB1 53/4885BDKRB2 677/4885ELANE 805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.