SCHEMBL676110

SCHEMBL676110

CN1C(=O)C2CC=CCC2C1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.50
ALDH1A1 P00352 5/20 0.47
LMNA P02545 3/20 0.47
TSHR P16473 3/20 0.47
HSD17B10 Q99714 3/20 0.47
TP53 P04637 3/20 0.47
KMT2A Q03164 2/20 0.47
HPGD P15428 2/20 0.47
CYP3A4 P08684 1/20 0.47
ALOX15 P16050 1/20 0.47
MAPK1 P28482 1/20 0.47
HTT P42858 1/20 0.47
HIF1A Q16665 1/20 0.47
POLB P06746 2/20 0.46
TDP1 Q9NUW8 3/20 0.44
CA9 Q16790 3/20 0.41
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
ACHE P22303 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2661927 1.00 NPSR1 (0.50) NPSR1ALDH1A1LMNATSHRHSD17B10
SCHEMBL23900410 0.90 NPSR1 (0.42) NPSR1ALDH1A1LMNATSHRHSD17B10
SCHEMBL17532418 0.77 ALDH1A1 (0.57) ALDH1A1LMNATSHRHSD17B10TP53
SCHEMBL9906966 0.75 KMT2A (0.54) NPSR1ALDH1A1LMNAKMT2AHPGD
SCHEMBL22016051 0.75 ACHE (0.36) ALDH1A1LMNATSHRKMT2AMAPK1
SCHEMBL23379624 0.75 ACHE (0.36) ALDH1A1LMNATSHRKMT2AMAPK1
SCHEMBL11528994 0.74 ACHE (0.33) NPSR1ACHE
SCHEMBL16607543 0.74 ALDH1A1 (0.47) NPSR1ALDH1A1LMNATSHRHSD17B10
SCHEMBL21449886 0.74 ALDH1A1 (0.47) NPSR1ALDH1A1LMNATSHRHSD17B10
SCHEMBL17970089 0.74 ALDH1A1 (0.47) NPSR1ALDH1A1LMNATSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240210827-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR MANUFACTURING CURED RELIEF PATTERN, AND SEMICONDUCTOR APPARATUS ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-06-27 US disclosed
US-20240210827-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR MANUFACTURING CURED RELIEF PATTERN, AND SEMICONDUCTOR APPARATUS ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-06-27 US disclosed
US-11780946-B2 Alternating copolymer, method of producing alternating copolymer, method of producing polymeric compound, and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2023-10-10 US disclosed
US-11780946-B2 Alternating copolymer, method of producing alternating copolymer, method of producing polymeric compound, and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2023-10-10 US disclosed
US-20210230332-A1 ALTERNATING COPOLYMER, METHOD OF PRODUCING ALTERNATING COPOLYMER, METHOD OF PRODUCING POLYMERIC COMPOUND, AND METHOD OF FORMING RESIST PATTERN NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-07-29 US disclosed
WO-2021143677-A1 FUSED RING SUBSTITUTED AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION, AND USE THEREOF 青岛清原化合物有限公司 2021-07-22 WO disclosed
US-20200409263-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR MANUFACTURING CURED RELIEF PATTERN, AND SEMICONDUCTOR APPARATUS ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-12-31 US disclosed
US-10007164-B2 Organic compounds, light modulating composition and light modulating devices employing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2018-06-26 US disclosed
US-9918474-B2 Agents for combating plant pests BAYER INTELLECTUAL PROPERTY GMBH (DE) 2018-03-20 US disclosed
US-9918474-B2 Agents for combating plant pests BAYER INTELLECTUAL PROPERTY GMBH (DE) 2018-03-20 US disclosed
US-7232840-B2 Agents for combating plant pests BAYER CROPSCIENCE AG (DE) 2007-06-19 US disclosed
US-7232840-B2 Agents for combating plant pests BAYER CROPSCIENCE AG (DE) 2007-06-19 US disclosed
US-20070129520-A1 High yield of 2-formylethyldimethylsilanol-modified polydimethylsiloxane obtained by the continuous process of oxidizing 3-hydroxypropyldimethylsilanol-modified corresponding polymer using Tempoas an oxidation catalyst and air or oxygen as oxidizer in an aqueous dispersion; industrial scale; low cost WACKER CHEMIE AG (DE) 2007-06-07 US disclosed
US-20070129520-A1 High yield of 2-formylethyldimethylsilanol-modified polydimethylsiloxane obtained by the continuous process of oxidizing 3-hydroxypropyldimethylsilanol-modified corresponding polymer using Tempoas an oxidation catalyst and air or oxygen as oxidizer in an aqueous dispersion; industrial scale; low cost WACKER CHEMIE AG (DE) 2007-06-07 US disclosed
US-20070043086-A1 synergistic mixture of (2-chloropyridine)-(2-cyanoiminothiazolidine)-methyl and azolo-fingicidal compounds; fungicides, herbicides and insecticide; controlling plant pests ERDELEN CHRISTOPH 2007-02-22 US disclosed
US-20070043086-A1 synergistic mixture of (2-chloropyridine)-(2-cyanoiminothiazolidine)-methyl and azolo-fingicidal compounds; fungicides, herbicides and insecticide; controlling plant pests ERDELEN CHRISTOPH 2007-02-22 US disclosed
WO-2006071217-A1 FLAME RETARDANT POLYSTYRENE FOAM COMPOSITIONS ALBEMARLE CORPORATION (US) 2006-07-06 WO disclosed
WO-2006071214-A1 FLAME RETARDANT EXTRUDED POLYSTYRENE FOAM COMPOSITIONS ALBEMARLE CORPORATION (US) 2006-07-06 WO disclosed
EP-0399351-A2 Epoxy resin and water borne coatings therefrom THE DOW CHEMICAL COMPANY (US) 1990-11-28 EP disclosed
US-4946911-A CONTAINING UNSATURATED IMIDE THE DOW CHEMICAL COMPANY (US) 1990-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10007164-B2 Organic compounds, light modulating composition and light modulating devices employing the same CRY1, XDH, CHRM1 NPSR1 3626/4885ALDH1A1 999/4885LMNA 1383/4885
US-20070043086-A1 synergistic mixture of (2-chloropyridine)-(2-cyanoiminothiazolidine)-methyl and azolo-fingicidal compounds; fungicides, herbicides and insecticide; controlling plant pests SPHK2, GRM2, DHFR NPSR1 4191/4885ALDH1A1 2729/4885LMNA 3604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.