SCHEMBL17864111

SCHEMBL17864111

c1ccc(-c2nc(-c3ccccc3)nc(-n3c4ccccc4c4cc5c(ccc6c7ccccc7ccc56)cc43)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
HSD17B10 Q99714 2/20 0.39
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
MAPT P10636 3/20 0.38
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
RECQL P46063 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HPRT1 P00492 3/20 0.37
HPGD P15428 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
CYP11B1 P15538 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17864125 0.93 RAC2 (0.35) ALDH1A1HSD17B10HIF1ACYP1B1MAPT
SCHEMBL26010333 0.91 MAPT (0.36) ALDH1A1HSD17B10HIF1ACYP1B1MAPT
SCHEMBL26007228 0.91 TUBB4A (0.37) ALDH1A1HSD17B10HIF1ACYP1B1MAPT
SCHEMBL23759461 0.89 MAPT (0.40) ALDH1A1HSD17B10HIF1ACYP1B1MAPT
SCHEMBL17864113 0.88 ALDH1A1 (0.38) ALDH1A1HSD17B10HIF1ACYP1B1MAPT
SCHEMBL17864067 0.88 CYP1B1 (0.36) ALDH1A1HSD17B10HIF1ACYP1B1MAPT
SCHEMBL17864100 0.88 KDM4E (0.40) ALDH1A1HSD17B10HIF1ACYP1B1MAPT
SCHEMBL13086905 0.86 L3MBTL1 (0.39) ALDH1A1HSD17B10MAPTNPC1LMNA
SCHEMBL16302971 0.86 L3MBTL1 (0.39) ALDH1A1MAPTLMNAHPGDL3MBTL1
SCHEMBL10018650 0.86 L3MBTL1 (0.41) ALDH1A1MAPTLMNAHPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016099037-A2 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2016-06-23 WO disclosed