Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MLYCD | O95822 | 1/20 | 0.48 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17865381 | 0.89 | HPGD (0.57) | MLYCDHPGDNPSR1TRPV1EPHX2 | |
| SCHEMBL15839273 | 0.86 | RAF1 (0.46) | ROCK2ROCK1KMT2AGPR139GAA | |
| SCHEMBL17865389 | 0.85 | MRGPRX4 (0.53) | MAPK14POLB | |
| SCHEMBL17865382 | 0.84 | KMT2A (0.51) | KMT2AMEN1HPGDNPSR1GAA | |
| SCHEMBL17865393 | 0.81 | MRGPRX4 (0.51) | MAPK14KMT2ANR1H4 | |
| SCHEMBL15835747 | 0.79 | RAF1 (0.40) | KMT2AMEN1HPGDGAAHSD17B10 | |
| SCHEMBL17660263 | 0.79 | MLYCD (0.66) | KMT2AMLYCDHPGDNPSR1GAA | |
| SCHEMBL17865398 | 0.78 | ACACB (0.47) | ROCK2ROCK1KMT2AMEN1HPGD | |
| SCHEMBL15839324 | 0.77 | RAF1 (0.44) | ROCK2ROCK1GPR139 | |
| SCHEMBL15839264 | 0.77 | GPR132 (0.45) | ROCK2ROCK1GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10299475-B2 | Pesticide | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2019-05-28 | — | — | US | disclosed |
| US-20160192651-A1 | PESTICIDE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2016-07-07 | — | — | US | disclosed |
| EP-3037408-A1 | HARMFUL ORGANISM CONTROL AGENT | Ishihara Sangyo Kaisha, Ltd. (JP) | 2016-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10299475-B2 | Pesticide | DDT, ACHE, KCNH1 | ROCK2 1150/4885ROCK1 1426/4885MAPK14 2209/4885 |
| US-20160192651-A1 | PESTICIDE | DDT, ACHE, KCNH1 | ROCK2 1150/4885ROCK1 1426/4885MAPK14 2209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.