Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 5/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10447550 | 0.76 | ADRA1D (0.47) | ADRA1DADRA1AADRA1BMEN1TSHR | |
| SCHEMBL10426987 | 0.73 | ADRA1D (0.45) | ADRA1DADRA1AADRA1BTHRB | |
| SCHEMBL9382556 | 0.72 | ADRA1D (0.49) | ADRA1DADRA1AADRA1B | |
| SCHEMBL13104453 | 0.70 | TSHR (0.42) | ADRA1DADRA1AADRA1BMEN1TSHR | |
| SCHEMBL817816 | 0.69 | ACHE (0.44) | ADRA1DADRA1AADRA1BMEN1TSHR | |
| SCHEMBL914478 | 0.69 | NOS2 (0.43) | ELANEALDH1A1MAPTTHRBSMN1; SMN2 | |
| SCHEMBL15096854 | 0.68 | ELANE (0.36) | ELANEALDH1A1MAPTTHRBSMN1; SMN2 | |
| SCHEMBL9737986 | 0.67 | ADRA1D (0.43) | ADRA1DADRA1AADRA1BMEN1TSHR | |
| SCHEMBL2776823 | 0.67 | TSHR (0.47) | MEN1TSHRCYP2C19RAB9AKMT2A | |
| SCHEMBL9176753 | 0.66 | UGT2B17 (0.38) | MEN1KMT2AELANEALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237547-B1 | DIRECT DYES AND COMPOSITION COMPRISING THE DYES | KAO GERMANY GMBH (DE) | 2019-03-20 | — | — | EP | disclosed |
| US-10196520-B2 | Direct dyes and composition comprising the dyes | KAO GERMANY GMBH (DE) | 2019-02-05 | — | — | US | disclosed |
| US-20170362436-A1 | DIRECT DYES AND COMPOSITION COMPRISING THE DYES | KAO GERMANY GMBH (DE) | 2017-12-21 | — | — | US | disclosed |
| EP-3237547-A1 | DIRECT DYES AND COMPOSITION COMPRISING THE DYES | Kao Germany GmbH (DE) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102207-A1 | DIRECT DYES AND COMPOSITION COMPRISING THE DYES | KAO GERMANY GMBH (DE) | 2016-06-30 | — | — | WO | disclosed |
| EP-3037485-A1 | Direct dyes and composition comprising the dyes | Kao Germany GmbH (DE) | 2016-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10196520-B2 | Direct dyes and composition comprising the dyes | KRT18, TUBB4A, BRDT | ADRA1D 4547/4885ADRA1A 4550/4885ADRA1B 4588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.