Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 5/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9382556 | 0.92 | ADRA1D (0.49) | ADRA1DADRA1AADRA1BITGB3ITGA2B | |
| SCHEMBL9737476 | 0.84 | ITGB3 (0.38) | ADRA1DADRA1AADRA1BITGB3ITGA2B | |
| SCHEMBL9737731 | 0.76 | TP53 (0.41) | ITGB3ITGA2BDGAT1TP53L3MBTL1 | |
| SCHEMBL7289455 | 0.76 | ITGB3 (0.36) | ADRA1DADRA1AADRA1BITGB3ITGA2B | |
| SCHEMBL9382468 | 0.75 | ITGB3 (0.42) | ADRA1DADRA1AADRA1BITGB3ITGA2B | |
| SCHEMBL10447550 | 0.73 | ADRA1D (0.47) | ADRA1DADRA1AADRA1BMEN1TSHR | |
| SCHEMBL7296944 | 0.72 | ITGB3 (0.33) | ADRA1DADRA1AADRA1BITGB3ITGA2B | |
| SCHEMBL10426987 | 0.70 | ADRA1D (0.45) | ADRA1DADRA1AADRA1B | |
| SCHEMBL8534684 | 0.69 | DGAT1 (0.50) | ITGB3ITGA2BDGAT1FFAR1 | |
| SCHEMBL467521 | 0.69 | ACHE (0.55) | DGAT1TP53L3MBTL1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153194-A | Anxiolytic agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0394471-A1 | THIENOCYCLOHEPTAPYRIDAZINE COMPOUNDS AND MEDICINAL USES THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |