SCHEMBL1786964

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1783816	0.87	KDR (0.46)	PKMKDRHSD17B10ALDH1A1KMT2A
	SCHEMBL1785320	0.84	KDR (0.63)	KDRHSD17B10ALDH1A1POLBALOX15
	SCHEMBL1941030	0.83	PKM (0.57)	PKMKDRHSD17B10ALDH1A1POLB
	Hydrochloric Acid SCHEMBL3924243	0.82	PKM (0.56)	PKMKDRHSD17B10ALDH1A1POLB
	SCHEMBL1784766	0.82	L3MBTL1 (0.45)	ALDH1A1TDP1KMT2AMEN1HPGD
	SCHEMBL1786652	0.79	KDR (0.45)	KDRALDH1A1KMT2AMEN1HPGD
	SCHEMBL1788060	0.78	RAB9A (0.53)	PKMALDH1A1POLBTDP1KMT2A
	SCHEMBL4017457	0.78	KDR (0.69)	PKMKDRHSD17B10ALDH1A1POLB
	SCHEMBL1496331	0.78	PKM (0.56)	PKMKDRHSD17B10ALDH1A1POLB
	SCHEMBL1942084	0.76	PKM (0.54)	PKMKDRHSD17B10ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.