Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Fluoride Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL1708171 | 0.95 | LMNA (0.38) | — | |
| SCHEMBL5475203 | 0.95 | LMNA (0.38) | — | |
| Fluoride Ion SCHEMBL29196501 | 0.95 | — | — | |
| Fluoride Ion SCHEMBL8500720 | 0.95 | — | — | |
| Fluoride Ion SCHEMBL6275280 | 0.95 | SLC34A1 (0.36) | — | |
| Fluoride Ion SCHEMBL6846212 | 0.91 | — | — | |
| Fluoride Ion SCHEMBL20723412 | 0.91 | — | — | |
| Fluoride Ion SCHEMBL10608996 | 0.91 | — | — | |
| SCHEMBL9138380 | 0.91 | LMNA (0.40) | — | |
| SCHEMBL1615261 | 0.91 | LMNA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237068-A1 | MINERALIZATION FLUORIDE COMPOSITIONS | The University Of Melbourne (AU) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016101041-A9 | MINERALIZATION FLUORIDE COMPOSITIONS | THE UNIVERSITY OF MELBOURNE (AU) | 2016-07-28 | — | — | WO | disclosed |
| WO-2016101041-A1 | MINERALIZATION FLUORIDE COMPOSITIONS | THE UNIVERSITY OF MELBOURNE (AU) | 2016-06-30 | — | — | WO | disclosed |