Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Fluoride Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL1708171 | 1.00 | LMNA (0.38) | — | |
| Fluoride Ion SCHEMBL20723412 | 0.95 | — | — | |
| Fluoride Ion SCHEMBL6846212 | 0.95 | — | — | |
| Fluoride Ion SCHEMBL10608996 | 0.95 | — | — | |
| Fluoride Ion SCHEMBL17870658 | 0.95 | — | — | |
| SCHEMBL1615261 | 0.95 | LMNA (0.40) | — | |
| SCHEMBL9138380 | 0.95 | LMNA (0.40) | — | |
| SCHEMBL30537706 | 0.95 | LMNA (0.40) | — | |
| Sodium Monofluorophosphate SCHEMBL93758 | 0.95 | — | — | |
| SCHEMBL3799586 | 0.95 | LMNA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958445-A | ORGANOLEPTICALLY ACCEPTABLE ANTIINFLAMMATORY AGENT;VETERINARY DRUG; FOR ORAL ADMINISTRATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-09-28 | — | — | US | disclosed |
| US-5780046-A | ADMINISTERING IN COMBINATION WITH AN ACIDIC COMPONENT TO IMPROVE TASTE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-07-14 | — | — | US | disclosed |
| US-4460565-A | CONTAINING FLUORIDE COMPOUND, SOLUBLE PHOSPHATE, AND CALCIUM SALT | INTRADAL N.V. (NL) | 1984-07-17 | — | — | US | disclosed |