Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28645675 | 0.88 | TRPA1 (0.31) | TYMP | |
| SCHEMBL28645676 | 0.88 | TRPA1 (0.31) | TYMP | |
| SCHEMBL17870761 | 0.78 | CDK9 (0.39) | — | |
| SCHEMBL17870756 | 0.72 | ADORA2B (0.31) | — | |
| SCHEMBL19873806 | 0.72 | ALDH1A1 (0.33) | — | |
| SCHEMBL28644025 | 0.72 | CDK9 (0.38) | — | |
| SCHEMBL28649422 | 0.65 | USP5 (0.32) | — | |
| SCHEMBL8579242 | 0.65 | TP53 (0.58) | — | |
| SCHEMBL28663372 | 0.62 | ADORA2B (0.30) | — | |
| SCHEMBL28645677 | 0.61 | USP5 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237403-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102882-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-06-30 | — | — | WO | disclosed |