SCHEMBL28645676

SCHEMBL28645676

CC(C(=O)O)n1cc(Br)c(=O)n(CC[C@H]2CO2)c1=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.31
KDM4E B2RXH2 1/20 0.31
TYMP P19971 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28645675 1.00 TRPA1 (0.31) TRPA1KDM4ETYMP
SCHEMBL17870816 0.88 TYMP (0.31) TYMP
SCHEMBL28649422 0.79 USP5 (0.32)
SCHEMBL17870761 0.76 CDK9 (0.39) KDM4E
SCHEMBL28645677 0.75 USP5 (0.31)
SCHEMBL28663372 0.75 ADORA2B (0.30)
SCHEMBL28644025 0.72 CDK9 (0.38) KDM4E
SCHEMBL19873806 0.72 ALDH1A1 (0.33)
SCHEMBL28645672 0.69 USP5 (0.33)
SCHEMBL28645673 0.69 USP5 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107428744-B Novel heterocyclic compounds and their use in medicine and cosmetics 盖尔德马研究及发展公司 2021-09-24 CN disclosed